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USP7 activates PTH1R. 2 / 2

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"Collectively, these results demonstrate that Ihh/Smo promotes PTHrP/PTH1R signalling to modulate chondrocyte proliferation and chondrogenic differentiation but Ihh/Smo enhances the hypertrophic differ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Our study found that USP7 knockdown or inhibition activated Ihh/Smo signalling and inhibited PTHrP/PTH1R signalling, resulting in upregulation of hypertrophy."

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USP7 activates PTH1R. 2 / 2

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