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Hedgehog increases the amount of USP48. 2 / 2

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"In addition, we find that the Sonic Hedgehog (SHH) pathway induces USP48 expression through Gli1 mediated transcriptional activation, which forms thus a positive feedback loop to regulate Hh signaling."

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"USP48 provides a positive feedback loop in Hh signaling as USP48 expression is induced by Hh activation."

30754706

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IndraLab

Statements

Hedgehog increases the amount of USP48. 2 / 2

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