IndraLab

Statements

USP27X activates Neoplasms. 4 / 4
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"Importantly, dox-induced depletion of USP27X significantly impaired further tumor development."
36001804
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"The results of this study indicate that knockdown of USP27X in MDA-MB-231 cells inhibits proliferation, whereas overexpression of USP27X in BT549 cells promotes tumor growth."
38030604
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"In vivo experiments also demonstrated that knockdown of USP27X suppressed tumor proliferation in xenograft models (Fig. 4F–H), while overexpression of USP27X promoted tumor proliferation in BT549 xenograft models (Fig. 4I–K)."
38030604
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"Collectively, we revealed that USP27 exerts tumor-promoting action by modulating the USP27–SETD3 axis.Studies have validated that USP22, the USP27 homologous protein, has similar effects with USP27 [16, 21, 22]."
35018513