IndraLab

Statements

USP8 activates SQSTM1. 3 / 3
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"The knockdown of USP8 promoted autophagic degradation of SQSTM1/p62 (p62), decreasing the p62 adaptor protein in HEK293T cells."
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"The knockdown of USP8 promoted autophagic degradation of SQSTM1/p62 (p62), decreasing the p62 adaptor protein in HEK293T cells."
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"In summary, USP8 inhibition has been shown to reduce the autophagy protein p62 during infection with Salmonella, which is correlated with increased autophagy flux.3 Discussion."
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