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USP4 inhibits epithelial to mesenchymal transition. 3 / 3

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"Through the immunoblotting analysis, we found that the knockdown of USP4 induced drastic down-regulation of N-cadherin and up-regulation of E-cadherin, indicating that USP4 deficiency could reverse the process of EMT."

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"USP4 deubiquitination maintains ACE2 stability and thus inhibits EMT and fibrosis in LUAD."

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"Researchers discovered that deubiquitinating USP4 (Ubiquitin-specific protease 4) keeps ACE2 stable, which in turn prevents EMT and fibrosis in LUAD."

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IndraLab

Statements

USP4 inhibits epithelial to mesenchymal transition. 3 / 3

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