IndraLab

Statements

FASN binds USP13. 6 / 6
2 | 4
sparser
"Mechanistically, USP13 interacts with fatty acid synthase (FASN) and enhances FASN protein stability."
35898882
sparser
"USP13 interacts with FASN to enhance its protein stability to promote fatty acid synthesis, cancer stemness and sphere formation. xref Inhibition of FASN resulted in the decrease of lipogenesis, self‐renewal ability and chemotherapy resistance in the cancer cells."
40621620
sparser
"We confirmed the interaction between endogenous USP13 and FASN by the co-immunoprecipitation (Co-IP) of H1048 cell lysates ( xref )."
35898882
sparser
"To detect the role of USP13-FASN axis in regulating cancer stemness and lipogenesis in SCLC, we stably depleted FASN after WT USP13 reconstitution in USP13 knockdown cells."
35898882
biogrid
No evidence text available
35898882
biogrid
No evidence text available
35898882