IndraLab

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MiR-17-5p inhibits KCNH2. 2 / 2
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"Finally, our whole-cell patch-clamp recordings demonstrated that transfection of miR-17-5p suppressed h-ERG current (I h-ERG) in HEK293 cell with stable h-ERG expression, an effect reversed by co-transfection of miR-17-5p-I, but not by the mutant inhibitor (XREF_FIG)."
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reach
"Upregulation of miR-17-5p in turn downregulates the related chaperones to reduce h-ERG trafficking leading to associated electrical disturbance of the heart."
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