IndraLab

Statements

TLR4 binds AGER and BSG. 2 / 2
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"Tasquinimod binds to S100A9 and inhibits its interaction with its receptors TLR4, RAGE, and CD147, reverting the stress-induced reactivation of dormant tumor cells in mice."
33268511
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"Tasquinimod is a small molecule with a quinoline-3-carboxamide structure that binds to S100A9 and blocks its interaction with TLR4, RAGE and EMMPRIN expressed on different subsets of myeloid cells. xref Tasquinimod has been shown to exert immunomodulatory, anti-angiogenic and anti-metastatic properties in preclinical studies. xref "
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