Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

BSG binds TLR4 and AGER. 2 / 2

| 2

➶

sparser

"Tasquinimod is a small molecule with a quinoline-3-carboxamide structure that binds to S100A9 and blocks its interaction with TLR4, RAGE and EMMPRIN expressed on different subsets of myeloid cells. xref Tasquinimod has been shown to exert immunomodulatory, anti-angiogenic and anti-metastatic properties in preclinical studies. xref "

27471612

➶

sparser

"Tasquinimod binds to S100A9 and inhibits its interaction with its receptors TLR4, RAGE, and CD147, reverting the stress-induced reactivation of dormant tumor cells in mice."

33268511

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...