IndraLab

Statements


USP25 activates FOXP3. 2 / 2
| 2

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"USP21 prevents FOXP3 degradation through deubiquination, thus stabilizing Treg phenotype and antagonizing the development of Th1 like Tregs [XREF_BIBR]."

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"Similarly, USP21 prevents Foxp3 degradation by deubiquitinating K48-type modifications at residues Lys 206, Lys 216, Lys 227, Lys 252, Lys 277, Lys 332, and Lys 393."