IndraLab

Statements


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sparser
"Since phosphacan can interact with N-CAM and Ng-CAM."

sparser
"Immunohistological and cell biological results suggested that neurocan regulates neurite outgrowth through specific binding to N-CAM and Ng-CAM at the surface of neurons."

sparser
"The interaction of phosphacan and N-CAM or Ng-CAM leads to an reduced neurite outgrowth and adhesion in vitro [ xref ]."

sparser
"For example, the binding of phosphacan to N-CAM and Ng-CAM was not significantly reduced by ChABC treatment, and phosphacan lacking GAG chains still bound to neurons and inhibited neurite growth comparable to intact phosphacan ( xref ; xref )."

sparser
"Neurocan, another CSPG in the CNS matrix, also binds to N-CAM and Ng-CAM, and inhibits the neurite outgrowth [ xref ]."

sparser
"Neurocan was shown to inhibit cell adhesion and neurite outgrowth of neurons isolated from chick embryo brains, possibly by binding to the cell adhesion molecules Ng- CAM and N-CAM [19]."