IndraLab

Statements

EZH2 activates USP7. 3 / 3
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reach
"While the relationship between USP7 and EZH2 and its significance in NB pathogenesis have not yet been established, our results have shown direct correlations between USP7 downregulation induced by inhibition of its deubiquitinase activity via Almac4 or by USP7 depletion and EZH2 and N-Myc ubiquitination and protein degradation."
37762082
reach
"Herein, we identified that EZH2 is a deubiquitination target of USP7 and that EZH2 protein stability is increased by USP7."
32453339
reach
"To further address the regulatory mechanism underlying EZH2 protein stabilization by USP7, we examined whether EZH2 is a deubiquitination target of USP7."
32453339