IndraLab

Statements

USP10 activates SQSTM1. 4 / 4
| 4
reach
"In addition to USP10-WT, USP10 96-798, but not USP10 1-116, increased the size of p62 aggregates and aggresomes (XREF_FIG E and 5F)."
30469013
reach
"USP10, by interacting with p62, further augments p62-induced ubiquitinated protein aggregation and then stimulates the transport of p62/ubiquitinated protein aggregates to the perinuclear aggresome-forming site."
31501480
reach
"In addition, USP10 stimulates the transport of multiple p62-positive ubiquitinated protein aggregates to the perinuclear region to form one big aggregate (aggresome)."
31501480
reach
"These results suggested that USP10 functions to stimulate transport of p62 aggregates to the perinuclear aggresome formation site."
30469013