IndraLab

Statements

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"The antimalarial hydroxychloroquine (HCQ) is frequently used for the treatment of SLE and is supposed to inhibit the conversion of 25 (OH) D in 1,25 (OH) 2 D by inhibiting the enzyme hydroxylase alpha1."
28900675
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"HCQ might inhibit the conversion of 25-(OH)-vitamin D to 1,25-(OH)2-vitamin D."
35186126
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"HCQ possibly inhibited the conversion of 25(OH)D to metabolically active form of vitamin D (1, 25(OH)2D) [ 91 ]."
31520805
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"Huisman et al. [XREF_BIBR] found lower 1,25 (OH) 2 D 3 levels in patients with lupus treated with HCQ, although circulating 25 (OH) D levels did not differ between treated and untreated patients."
22129903
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"Huisman and al. found lower 1,25 (OH) 2D concentration in SLE patients treated with hydroxychloroquine and no significant difference in 25 (OH) D concentration among patients who use hydroxychloroquine and those who did not [XREF_BIBR]."
27275231
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"Hydroxychloroquine also impairs 25 (OH) D3-1-alpha-hydroxylase, and therefore, it is often chosen to treat hypercalcemia."
33329511
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"XREF_BIBR The antimalarial, HCQ, which is frequently used for the treatment of SLE, might impair vitamin D status in patients with lupus, since HCQ is supposed to inhibit the conversion of 25 (OH) D in 1,25 (OH) 2 by inhibiting the enzyme hydroxylase alpha1."
26557383
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"Hydroxychloroquine prescribed in several autoimmune diseases may inhibit the conversion of 25 (OH) D to 1,25 (OH) 2 D."
21047669
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"In contrast, within 5 days 400 mg of hydroxychloroquine daily lowered elevated levels of calcium and 1,25-(OH) 2D by 37% and 72%, respectively, in a hypercalcemic patient with sarcoidosis."
10022456
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"Hydroxychloroquine has been suspected to inhibit the conversion of 25 (OH) D to its biologically more active form 1,25-dihydroxyvitamin D, and as such, Ruiz-Irastorza et al reported that hydroxychloroquine was associated with higher 25 (OH) D levels."
24470118
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"The potent antioxidant properties observed for the Schiff-bases in this test in comparison to the other hydroxyquinoline derivatives are likely due to the negative inductive effect of the Cl and I rin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
25019963
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"Hydroxychloroquine is suspected to inhibit the conversion of 25 (OH) D to its more biologically active form 1,25 (OH) 2 D but has also been found to protect against vitamin D deficiency."
19790113