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Ketamine inhibits KCNH2. 2 / 2
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"3 , 4 , 9 On the other hand, the QT interval in the ketamine/xylazine-anesthesia group was longer than that of our previous study using the urethane-anesthetized guinea pigs (132 ± 5 ms), 16 which may[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"WT hERG is blocked in a concentration dependent manner with IC50 = 12.05 +/-1.38 mum by ketamine, and the steady-state inactivation curves are shifted to more negative potentials (about -27 mV)."
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