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OTULIN activates necroptotic process. 2 / 2

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"Phosphorylation of OTULIN regulates RIPK1 ubiquitination and promotes necroptosis (8)."

34797715

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"OTULIN hyper-phosphorylation promotes necroptosis by locking ring finger protein 31 (RNF31, also known as HOIP) away from the cylindromatosis (CYLD) complex, resulting in altered receptor interacting serine/threonine kinase 1 (RIPK1) ubiquitination."

32944611

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Statements

OTULIN activates necroptotic process. 2 / 2

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