IndraLab

Statements


USP9X deubiquitinates BCL9. 3 / 4
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"Additionally, the deubiquitination of BCL9 by USP9X increases proliferation and invasion of breast cancer cells."

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"278 The deubiquitination of BCL9 by USP9X facilitates the assembly of the β-catenin-BCL9-PYGO complex, thereby augmenting the transcriptional activity of Wnt/β-catenin target genes."

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"The USP9X mediated BCL9 deubiquitination promotes formation of the beta, catenin, BCL9, and PYGO complex, increasing the transcriptional activity of the Wnt and beta-catenin target genes."