IndraLab
Statements
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"These data concluded that co-expression of USP7 enhanced the stability of KDM6B to promote the KDM6B expression."
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"Combining previous studies with our results, a regulatory network could be proposed in the antagonizing atherosclerosis progression that depletion of miR-15b promoted USP7 expression to up-regulate KDM6B."
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eidos
"This proved that FOXO6 upregulates the expression of JMJD3 and CLU by mediating USP7 , which was confirmed by observations of neoplasia growth in vivo ."
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"37 , 38 In addition , a recent study has confirmed that USP7 could promote KDM6B expression by enhancing KDM6B stability ."
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eidos
"USP7 , importantly , strengthened the stability of KDM6B and promoted KDM6B expression ."
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"Based on these reports, we speculated that the USP7 mediated JMJD3 and CLU axis may be involved in the regulation of FOXO6 in EC."
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eidos
"Combining previous studies with our results , a regulatory network could be proposed in the antagonizing atherosclerosis progression that depletion of miR-15b promoted USP7 expression to up-regulate KDM6B ."
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"Additionally, the present study confirmed that USP7 enhanced the stability of KDM6B to promote KDM6B expression."
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"The occurrence of lupus nephritis is regulated by USP7 mediated JMJD3 stabilization."
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"These data supported our proposal that USP7 targeted JMJD3 for deubiquitination to improve JMJD3 protein stability."
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"37 In this study, we found that USP7 enhanced the stability of KDM6B to promote KDM6B expression inhibited the ubiquitination, while miR-15b inhibits USP7 expression in osteoporosis."