IndraLab

Statements

SMO binds USP8 and RACK1. 3 / 3
| 3
sparser
"In the presence of Hh, Hh dissociates Ci–Rack1 interaction, and promotes Rack1 forming a trimeric complex with Usp8 and Smo, resulting in Smo deubiquitination and cell surface accumulation (Fig.  xref )."
32467643
sparser
"The two-step co-IP assay showed that Usp8, Rack1, and Smo formed a trimeric complex (Fig.  xref )."
32467643
sparser
"In the presence of Hh, Rack1 dissociates from Ci–Rack1–Cos2 complex and forms a trimeric complex with Smo and Usp8, leading to Smo deubiquitination and cell surface accumulation."
32467643