IndraLab

Statements


Mice activates TNFAIP3. 2 / 2
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"Trib3 Tnfaip3 Lyz2 mice were produced by intercrossing Tnfaip3 Lyz2 mice with Trib3 mice."

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"In conclusion, these data indicate that mice harboring TNFAIP3‐deficient Langerin cDC1s especially displayed increased numbers of IFNγ‐producing CD8 T cells upon either a single HDM exposure or repetitive exposure with HDM.3.5 Blockade of IFNgamma restores eosinophilic airway inflammation in Tnfaip3 Lg-KO mice."