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"For example, hERG1 potassium channels have been shown to drive PDAC tumor malignancy [XREF_BIBR], the neurotransmitter GABA was identified as a promising agent for the prevention of PDAC in individuals at risk due to chronic alcohol consumption [XREF_BIBR], the transient receptor potential melastatin related 7 channel was found to regulate tumor migration [XREF_BIBR], the store operated calcium channels (SOCs) were shown to contribute to PDAC apoptosis resistance [XREF_BIBR] while the P2x7 receptor regulates cell survival, migration and invasion [XREF_BIBR]."