IndraLab

Statements

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"USP27X modulates tumor chemoresistance and invasion through deubiquitination and stabilization of Snail1 XREF_BIBR."
33391500
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"Furthermore, evidence from in vitro and in vivo studies revealed that depletion of USP27 inhibited HCC cell proliferation, invasion, metastasis and tumorigenesis, and that overexpression of SETD3 rescued this phenotype."
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"Conversely, overexpression of USP27 evidently enhanced cell invasion."
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"Taken together, these data revealed that knockdown of USP27 or SETD3 prevents liver cancer cell migration and invasion."
35018513
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"USP27X promotes the proliferation, invasion, and metastasis of BC cells by up-regulating CBX2."
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"Upregulation of USP27 in hepatocellular carcinoma patients leads to elevated SETD3 expression and increased cell proliferation, invasion, migration and tumorigenesis."
35018513
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"Transwell assay and wound‐healing assay indicated that the impaired migration and invasion ability caused by USP27X‐AS1 knockdown could be reversed by AKT overexpression (Figure 6M,N,Q,R and Figure S9A,C)."
38279869
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"Transwell and wound‐healing assays indicated that USP27X‐AS1 overexpression enhanced the migration and invasion abilities of HLF and Hep3B cells (Figure 2G–J and Figure S3G–J), whereas USP27X‐AS1 knockdown diminished these capabilities in MHCC97H and LM3 cells (Figure 2G–J and Figure S3G–J)."
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