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USP22 inhibits CDH1. 2 / 2

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"Immunoblot analysis confirmed that USP22 knockout upregulated E-cadherin, p16; reduced ALDH1A3, Cyclin E1, c-Myc, and attenuated activation of AKT and ERK pathways in these cells."

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"USP22 downregulation significantly increased the expression of E-cadherin ( epithelial marker ) but decreased the expression of N-cadherin and vimentin ( mesenchymal markers ) ( Fig. 4 ) ."

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IndraLab

Statements

USP22 inhibits CDH1. 2 / 2

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