IndraLab

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USP7 bound to MDM2 activates MDM2. 3 / 3

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"Daxx promotes the binding of MDM2 to HAUSP and thus increases MDM2 stability."

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"37 For instance, death domain associated protein (Daxx) promotes the binding of USP7 to Mdm2 and enhances Mdm2‐dependent p53 degradation."

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"42 , 43 , 44 , 45 In addition, Daxx functions as an adaptor protein to facilitate binding of USP7 to Mdm2, preventing Mdm2 degradation."

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IndraLab

Statements

USP7 bound to MDM2 activates MDM2. 3 / 3

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