IndraLab

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USP18 ubiquitinates NOTCH1. 2 / 2

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"Given that knockdown of USP18 leads to increased K48-linked ubiquitination of proteins, we speculated that USP18 K48-linked ubiquitination of Notch1 and thus stabilizes Notch1."

33051403

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"Second, USP18 overexpression reduces the K48-linked ubiquitination level of Notch1, whereas USP18 silencing significantly increases the Notch1 K48-linked ubiquitination."

33051403

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IndraLab

Statements

USP18 ubiquitinates NOTCH1. 2 / 2

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