IndraLab

Statements

CGAS binds OTUD3. 9 / 9
5 | 4
reach
"At the same time, the same amount of HA-OTUD3 WT and HA-OTUD3 CA were captured in corresponding pull-down samples, meaning that more FLAG-cGAS was not pulled down due to the interaction between cGAS a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36966392
reach
"41 OTUD3-DNA interaction can lead OTUD3 to the cytosolic DNA complex and increase the association between cGAS and OTUD3, which is in agreement with the results of cGAS proximity labeling."
36966392
biogrid
No evidence text available
36966392
biogrid
No evidence text available
36966392
biogrid
No evidence text available
36966392
biogrid
No evidence text available
36966392
biogrid
No evidence text available
36966392
reach
"In addition, OTUD3 C76A catalytic mutation (as FLAG-OTUD3 CA) does not obviously affect the interaction between HA-cGAS and FLAG-OTUD3 ( Figure S3 C)."
36966392
reach
"This result could partially explain the enhanced association between OTUD3 and cGAS in cells under DNA activation ( Figures 3 B and 3C), and also supports that OTUD3 can be recruited to cGAS-DNA compl[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36966392