IndraLab

Statements

Amodiaquine inhibits HNMT. 5 / 5
2 | 2 1
tas
No evidence text available
22771008
reach
"HNMT exhibits high substrate specificity for histamine and is inhibited by its reaction products, as well as by the SH-group reagents p-chloromercuribenzoate and N-ethylmaleimide and by the antimalarial drugs quinacrine and amodiaquine [XREF_BIBR]."
28791419
tas
No evidence text available
18789706
reach
"Amodiaquine, quinacrine and 1,4-(tele)-methyl-HI weakly inhibited HMT activity ex vivo and they failed to alter HI levels in the rat brain."
3832018
sparser
"IC50 values for the inhibition of mouse kidney HNMT by amodiaquine and S-adenosyl-L-homocysteine were 1.67 and 11.8 microM, respectively."
1907425