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OTUD5 inhibits polyubiquitin chain. 3 / 3
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"It has been reported that OTUD5 could suppress the type I interferon dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein TRAF3."
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"OTUD5 (DUBA) is activated by phosphorylation ( Huang et al., 2012 ) and suppresses the type I interferon response by cleaving the polyubiquitin chain from tumor necrosis factor receptor-associated fac[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"DUBA, a member of the ovarian tumor (OTU) domain containing cysteine protease superfamily, was shown to suppress the type I IFN dependent innate immune response by cleaving the K63 polyubiquitin chain on TRAF3."
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