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BRD4 inhibits USP35. 1 / 1

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"Our results demonstrated that BRD4 inhibition with (+)-JQ-1 treatment significantly inhibited the ER+ breast tumors enhanced by USP35 overexpression, along with decrease of SLC7A11 protein level, and increase of 4-HNE protein levels (Fig. 7), supporting that BRD4 mediated USP35 inhibition of ferroptosis in ER+ breast tumors.Reported studies have shown SLC7A11 expression can be regulated at translational and post-translational levels ."

39820080

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BRD4 inhibits USP35. 1 / 1

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