IndraLab

Statements

USP6 increases the amount of SMAD4. 2 / 2
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reach
"Overexpressing miR-130a or inhibiting USP6 in UM MUM-2B and MUM-2C cell lines reduced Wnt, β-catenin, and EGFR expression, activated SMAD4 expression, and reduced UM cell motility and invasion in vitro [21]."
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reach
"USP6 was a target of miR-130a and the overexpression of miR-130a or inhibition of USP6 in UM MUM-2B and MUM-2C cell lines inhibited the expression of Wnt, β-catenin, and EGFR, and activated SMAD4 expression, while reducing UM cell migration and invasion abilities in vitro."
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