IndraLab

Statements


USP13 binds FBXL14 and MYC. 4 / 4
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"To further confirm the interaction between endogenous c-Myc and USP13 or FBXL14 in GSCs, c-Myc was immunoprecipitated from cell lysate of partially differentiated GSCs that were induced by serum acutely (2 d)."

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"USP13 and FBXL14 interact with c-Myc in glioma cells."

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"These results demonstrate that c-Myc interacts with USP13 and FBXL14 in glioma cells, indicating that deubiquitinase USP13 and the ubiquitin E3 ligase FBXL14 are potential regulators of c-Myc protein stability in GBM."

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"The interaction between c-Myc and USP13 or FBXL14 was validated in HEK293 cells coexpressing c-Myc and Flag-tagged USP13 or FBXL14."