IndraLab

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"Here, our in vitro and in vivo experimental data showed that overexpression of USP39 significantly enhanced PC cells proliferation, whereas knockdown of USP39 suppressed PC cells proliferation."
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"Cai et al. [52] reported that USP39 promotes PC cell apoptosis by regulating the AKT signaling pathway."
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"Although our results suggested that high USP39 expression was closely associated with PC, but the precise mechanism by which USP39 promotes the tumorgenesis of PC remains to be further explored."
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"As shown in Fig. 2 B–C, we found that USP39-overexpressing cells showed a significantly higher in vitro proliferation rate than vector-transfected cells and knockdown of USP39 obviously suppressed the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These data collectively indicate that USP39 promotes the tumorigenicity of PC cells in vitro and in vivo ."
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