IndraLab

Statements

USP15 deubiquitinates BMPR1A. 6 / 7
1 | 6
reach
"Here, we demonstrate that USP15 interacts with and deubiquitylates the type I BMP receptor ALK3."
24850914
reach
"We hypothesized that USP15 deubiquitylates ALK3, thereby opposing the effect of SMAD6 and its associated E3 ubiquitin ligases."
24850914
reach
"USP15 deubiquitylates ALK3."
24850914
reach
"We next asked whether USP15 can deubiquitylate ALK3 in cells."
24850914
reach
"It was shown that USP15 interacts with type I BMP receptors, including ALK3, co-localises with ALK3 at the membrane and deubiquitylates ALK3, thereby countering the inhibition of the BMP pathway caused by SMAD6 XREF_BIBR."
25007997
reach
"Here, we demonstrate that USP15 enhances BMP signalling by associating with and deubiquitylating the BMP type I receptor ALK3."
24850914