IndraLab

Statements

AIF1 inhibits KCNMA1. 5 / 5
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"These data suggest that G-1 directly suppresses BK channel activation and currents in cerebral arterial myocytes, BK channels being critically important in the regulation of myocyte membrane potential and arterial contractility."
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"In conclusion, G-1, the specific activator for GPER, directly inhibits BK channel activation in cerebral arterial myocytes."
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"G-1 elicited vasodilation, but reduced BK channel function, in pressurized, endothelium denuded cerebral arteries."
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"Our data indicate that G-1 inhibits BK channel activation at nanomolar concentrations through enhancements in BK channel mean close times."
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"G-1 reduced BK channel activation in cerebral arterial myocytes through elevations in BK channel mean close times."
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