IndraLab

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"Our findings provide the first demonstration of the USP2/LEF1 cascade that enhances the osteogenic differentiation of hBMSCs, broadening the field for the development of BMSCs as effective agents in osteoporosis therapy."
40301985
reach
"By studying USP2 and LEF1 expression alterations, we observed their roles in osteoporosis pathogenesis.Collectively, our study provides the first demonstration of the USP2/LEF1 cascade that enhances the osteogenic differentiation of hBMSCs, as illustrated in Fig. 7."
40301985
reach
"Moreover, increased USP2 expression reduced bone loss and enhanced osteogenic differentiation in OVX mice."
40301985