IndraLab

Statements

Hydroxychloroquine inhibits SARS-CoV-2 RNA. 7 / 7
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"A recent study reported a reduced detection of SARS-CoV-2 RNA in upper respiratory tract specimens from patients treated with hydroxychloroquine."
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"Gautret et al. also reported that Hydroxychloroquine alone or in combination with Azithromycin reduced the detection of SARS-CoV-2 RNA in upper respiratory tract specimens compared with the control group in an open label, non randomized clinical trial [XREF_BIBR] and showed a rapid decline in the detection of SARS-CoV-2 RNA in upper respiratory tract specimens and length of stay in highly contagious wards in his later observational study including 80 patients [XREF_BIBR]."
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"19 Gautret et al demonstrated that use of hydroxychloroquine in COVID-19 patients alone or in combination with azithromycin reduces detection of SARS-CoV-2 RNA in upper respiratory tract secretions."
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"Additionally, hydroxychloroquine in combination with azithromycin has been reported to reduce the detection of SARS-CoV-2 RNA in upper respiratory tract specimens compared to a non randomized control group but did not assess clinical benefit [XREF_BIBR], and in a recent randomized, controlled, open-clinical trial in China, lopinavir and ritonavir did not show promise for the treatment of hospitalized patients with COVID-19 and pneumonia [XREF_BIBR]."
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"150 In a clinical study involving 36 patients with COVID-19 , the use of hydroxychloroquine ( 200 mg three times a day for 10 days ) was shown to decrease SARS-CoV-2 RNA in nasopharyngeal samples compared to the control group on day 6 ( 70 % vs 12.5 % ) ."
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"Gautret et al. also reported that Hydroxychloroquine alone or in combination with Azithromycin reduced the detection of SARS-CoV-2 RNA in upper respiratory tract specimens compared with the control group in an open label, non randomized clinical trial [16] and showed a rapid decline in the detection of SARS-CoV-2 RNA in upper respiratory tract specimens and length of stay in highly contagious wards in his later observational study including 80 patients [11]."
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"Studies have been published that hydroxychloroquine has anti-cytokine storm properties.150 In a clinical study involving 36 patients with COVID-19, the use of hydroxychloroquine (200 mg three times a day for 10 days) was shown to decrease SARS-CoV-2 RNA in nasopharyngeal samples compared to the control group on day 6 (70% vs 12.5%).151 In this study, it has been shown that the use of azithromycin in combination with hydroxychloroquine has an additional benefit, however, has not produced sufficient methodological evidence."
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