IndraLab

Statements



sparser
"Intriguingly, OTUB1 inhibits UBC13 and UBE2D/2E-family E2 conjugating enzymes in a DUB activity-independent manner [ xref ]."

sparser
"Instead, OTUB1 binds and inhibits the RNF168-associated E2s (UBC13/UBE2N and E2s of the UBE2D/UBE2E families) through assembly of a pseudocleavage product in its catalytic site ( Juang et al., 2012 ; [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"OTUB1 also inhibits E2s of the UBE2D and UBE2E families."