IndraLab

Statements

USP3 binds REST. 12 / 12
3 | 1 8
biogrid
No evidence text available
37170124
sparser
"USP3 interacts with REST."
37170124
sparser
"The interaction between USP3 and REST was confirmed by immunoprecipitation and Duolink in situ proximity assays."
37170124
sparser
"As a functional consequence of the interaction between USP3 and REST, the half-life of REST protein was extended by the deubiquitinating activity of USP3 (Fig.  xref )."
37170124
sparser
"The deubiquitinase USP3 interacts with REST, stabilizing and prolonging the half-life of REST protein, thereby counteracting its ubiquitination in NB ( xref , xref )."
39391247
reach
"The interaction between USP3 and REST was confirmed by immunoprecipitation and Duolink in situ proximity assays."
37170124
sparser
"An anti-Flag antibody co-immunoprecipitated ectopically expressed Myc-REST along with Flag-USP3 and vice-versa in HEK293 cells (Fig.  xref A), indicating that USP3 interacts with REST."
37170124
biogrid
No evidence text available
37170124
biogrid
No evidence text available
37170124
sparser
"Furthermore, Duolink PLA was used to visualize in situ interaction between USP3 and REST using a standard immunofluorescence staining assay."
37170124
sparser
"Duolink analysis confirmed the interaction between USP3 and REST by showing the fluorescence signals (PLA dots), but no PLA dots were observed when neuroblastoma cells were stained with either USP3 or REST antibody alone (Fig.  xref C)."
37170124
sparser
"These results suggest that USP3 interacts with REST protein both exogenously and endogenously."
37170124