IndraLab

Statements

TP53 binds USP49. 13 / 13
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"Investigation of the mechanism revealed that USP49 interacts with the N terminus of p53 and suppresses several types of p53 ubiquitination."
29748582
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"In our study, we found that USP49 has a positive effect on the transcriptional activity and protein stability of p53 and that USP49 interacts with p53 and suppresses its ubiquitination."
29748582
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"In our study, we found that USP49 has a positive effect on the transcriptional activity and protein stability of p53 and that USP49 interacts with p53 and suppresses its ubiquitination."
29748582
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"USP49 interacts with p53."
29748582
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"USP49 interacts with p53."
29748582
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"We report that USP49 binds to and stabilizes p53 via deubiquitination."
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"We therefore performed a co-immunoprecipitation experiment in which Flag-USP49 and HA-p53 plasmids were separately transfected or co-transfected into 293T cells and potential interactions between Flag-USP49 and HA-p53 were examined."
29748582
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"USP49 binds, deubiquitinates and stabilizes p53 following DNA damage, leading to p53 activation and apoptosis."
32201366
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"We also evaluated interaction between endogenous USP49 and p53 in HCT116 and U2OS cells using a p53 specific antibody."
29748582
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"We next assessed whether USP49 binds to p53."
29748582
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"Confocal laser scanning microscopy showed colocalization of p53 and USP49 (Fig.  xref ), raising the possibility that USP49 and p53 interact directly."
29748582
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"We also evaluated interaction between endogenous USP49 and p53 in HCT116 and U2OS cells using a p53-specific antibody (Fig.  xref )."
29748582
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"We next assessed whether USP49 binds to p53."
29748582