IndraLab

Statements

ROR2 binds WNT11. 6 / 6
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sparser
"Using co-immunoprecipitations, we verified the interaction of ROR2 with the identified ligand, WNT11."
34911552
reach
"Wnt5a and Wnt11 binding to FZD and/or RoR2 also can lead to intracellular Ca 2+ release, which activates Ca 2+ / calmodulin dependent kinase II (CaMKII) and protein kinase C (PKC) 32."
29453334
sparser
"Co-immunoprecipitation confirmed that WNT11 indeed interacts with the cysteine-rich domain of ROR2 and triggers its invasion-promoting signaling via RHO/ROCK."
34911552
reach
"Ror2 physically interacts with Wnt11."
24928507
sparser
"Ror2 physically interacts with Wnt11."
24928507
reach
"Binding of Wnt4, Wnt5a or Wnt11 to Fz and non canonical Fz co-receptors such as RYK, and ROR2, activates the Rho and Rac GTPases, leading to cytoskeletal modifications."
28522145