IndraLab

Statements

reach
"Conclusions : Eag1 may promote osteosarcoma cell proliferation and invasion by targeting STAT3-VEGF pathway and may be a potential therapeutic target for osteosarcoma."
27998439
reach
"Kv10.1 also aids cell cycle progression by stabilizing the membrane potential in the G1 phase and enhances invasiveness by modulating focal adhesions (Hartung, 2011)."
40110186
reach
"The results demonstrated that Eag1 siRNAs lead to reduced adhesion, migration, and invasion of MG-63 and Saos-2 cells."
26783521
reach
"The inhibition of Kv10.1 expression can up-regulate miR-126, thereby reducing the invasiveness of BC cells (20)."
36703789
reach
"On the other hand, Eag1 has also been shown to promote the migration and invasion of tumor cells via promoting the formation of pseudopodia (50)."
37654193
reach
"We found that KCNH1 knockdown decreased the migration, invasion, and proliferation of RA FLSs ( Fig. 6 A-D)."
34700130
reach
"Finally, we tried to explain the detailed mechanisms by which OS cell adhesion, migration, and invasion are inhibited by specific blockade of Eag1."
26783521
reach
"Circ_0016347 and KCNH1 promoted proliferation, migration, invasion, and glycolysis of OS cells."
33764794
reach
"KCNH1 knockdown reduced proliferation, migration, invasion and expression of MMP-1 and MMP-13 in RA FLSs."
34700130
reach
"Based on the findings in previous studies that potassium voltage gated channel subfamily H member 1 (KCNH1) was overexpressed in osteosarcoma and promoted the proliferation and invasion of osteosarcoma [XREF_BIBR - XREF_BIBR] and on our profile of the miRanda, PITA, RNAhybrid databases to explore the corresponding circRNAs of KCNH1, we speculated that hsa-circ-0016347 may be a potential regulator of osteosarcoma progression."
28424426