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KCNMA1 inhibits exocytosis. 3 / 3
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"We found that the introduction of the slo-1(eg142) null mutation into cim147[GFP::unc-2DA] animals reduced the intensity of the UNC-2DA puncta to levels comparable to those of WT animals (Fig. 4 A and B), indicating that an increase in synaptic transmission has a negative effect on UNC-2 channel abundance.TOM-1/Tomosyn negatively regulates SV exocytosis through its interaction with the SNARE complex (34, 35, 53, 54)."
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"When capacitated human sperm were SLO permeabilized, treated with His 6 -tagged BoNT and E-LC to prevent exocytosis, and subjected to indirect immunofluorescence with the PY20 antiphosphotyrosine anti[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"(C, D) Capacitated SLO-permeabilized human sperm were treated with 100 nM botulinum toxin B to prevent exocytosis, loaded with the fluorescent calcium indicator Fluo3-AM (2 μM) and treated with (D) or[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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