A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

RHEB binds RPTOR and MTOR. 2 / 2
| 2
sparser
"Whether TSC1/2 and/or Rheb binds to the mTOR complex containing raptor and modulates the signaling function and kinase activity of mTOR remains an important but unanswered question."
sparser
"In addition to directly phosphorylating mTOR, AKT also phosphorylates TSC2, which results in a Rheb-mediated interaction between mTOR and Raptor (regulatory associated protein of mTOR) to create mTOR complex 1 (mTORC1)."