IndraLab

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"Consequently, our findings imply that EBN attenuated the inflammatory response by reducing the expression of the NLRP3 inflammasome.3.4 EBN induces repair of the damaged alveolar epithelial layer by promoting the proliferation and viability of epithelial cells."
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"These results indicated that EBN pretreatment could resist inflammation and protect colonic tissues by reducing the infiltration of neutrophils and levels of pro-inflammatory cytokines.Three unique components including a thick luminal mucin layer, a single epithelial cell barrier, and secretion of anti-inflammatory factors can protect the gut mucosal lamina propria from luminal resident microbiota (Ueno et al., 2018)."
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"In conclusion, EBN inhibited NLRP3 expression in vitro.3.7 EBN regulates pulmonary inflammation by regulating the NF-kappaB pathway."
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"However, EBN intervention (especially high‐dose EBN) effectively reduced the degree of injury and the infiltration of inflammatory cells, which was consistent with the recent evidence showing that EBN inhibits inflammation and regulates the immune balance in mice with lung injury (Zeng et al., 2022)."
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"However, in some cases, the addition of a Kv7.2 channel opener did in fact reduce inflammation-induced increases in the excitability of DRG neurons based on in vitro models of persistent peripheral neuropathic pain (Cisneros et al., 2015)."
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"In addition, our cell experiments showed that EBN attenuated cigarette smoke-induced pulmonary inflammation mainly by inhibiting the tumor necrosis factor receptor 1 (TNFR1)/nuclear factor-kappa B (NF-kappaB)/NLRP3 pathway."
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"Moreover, experimentally induced inflammation and oxidative stress in rats were significantly attenuated by EBN treatment upon analyzing the total antioxidant status and inflammatory markers [40,41]."
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"The results showed that EBN could reduce the oxidative stress and inflammation triggered by HFD via transcriptional control of hepatic antioxidant gene expression related to inflammation."
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"This suggests that EBN alleviated systemic inflammation in the body in a dose‐dependent manner.Furthermore, as smoking causes direct harm to the lungs, we investigated whether EBN might reduce inflammation at the site of injury."
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