IndraLab

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EVC ubiquitinates USP48. 2 / 2
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"Besides USP7, we also tested the effect on EVC ubiquitination of USP48, another deubiquitinating enzyme known to regulate Hh signaling ( xref ; xref )."
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"Altogether, these data indicate that EVC proteins undergo ubiquitination, which is unaffected by USP7 but strongly depends on whether EVC-EVC2 find each other to form their heterodimeric and mutually stabilizing complex.Besides USP7, we also tested the effect on EVC ubiquitination of USP48, another deubiquitinating enzyme known to regulate Hh signaling (Zhou et al., 2017; Sanchez-Bellver et al., 2022)."
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