IndraLab

Statements

COPS6 activates Snail1. 7 / 7
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"We then validated whether ubiquitination is involved in CSN6 mediated Snail1 regulation."
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"The above results suggest that CSN6 promotes Snail1 stability via impeding ubiquitination of Snail1."
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"On the basis of our data, it is possible that CSN6 mediated Snail1 stabilization may be a common feature of various types of cancer."
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"CSN6 promotes the cell migration of breast cancer cells by positively regulating Snail1 stability."
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"Ubiquitination assay was performed to validate whether ubiquitination is involved in the upregulation of Snail1 by CSN6."
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"Taken together, these results indicated that CSN6 promotes Snail1 stability through reducing ubiquitination."
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"Our study showed that CSN6 prevented Snail1 degradation via proteasomal degradation."
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