IndraLab

Statements

Haem inhibits EIF2AK1. 2 / 2
| 2
reach
"In this manner, SIFI turns off the ISR after a specific stress (that is, mitochondrial import defects) has been addressed, even though HRI can also be activated by protein aggregation, haem depletion or pathogen infection ."
38297121
reach
"Importantly, we identified that two pathways, one mediated by haem‐regulated inhibitor (HRI)/eIF2α and another by the RNase angiogenin (ANG), jointly convey this neuron‐specific shift to secure translational control during ER stress."
35791631