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USP3 deubiquitinates CHEK1. 1 / 1

1 |

"Herein, we show that the K63-linked ubiquitin chain at CHK1's K132 residue has an inhibitory effect on the kinase activity. Furthermore, we demonstrate that this modification can be removed by ubiquitin-specific protease 3 (USP3), a deubiquitinating enzyme that targets K63-linked ubiquitin chains."

29735693

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USP3 deubiquitinates CHEK1. 1 / 1

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