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Modified MBD2 increases the amount of SCN3A. 2 / 2

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"In seizure induced mice, MBD2 expression was increased, which correlated with decreased CpG methylation, and enhanced SCN3A expression."

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"We further showed that VPA downregulated the expression of methyl-CpG-binding domain protein 2 (MBD2) at the posttranscriptional level and knockdown of MBD2 increased Scn3a expression."

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IndraLab

Statements

Modified MBD2 increases the amount of SCN3A. 2 / 2

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