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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TSPY1 activates USP7. 2 / 2

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"These findings provide the first evidence that TSPY1, in addition to TSPYL5, can promote the ubiquitin mediated degradation of USP7, suggesting TSPYL5 independent regulation of USP7 mediated p53 function by TSPY1."

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"Correspondingly, it is highly possible that the regulation of USP7 mediated p53 function by TSPY1 is an important molecular mechanism underlying its function in human spermatogenesis."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...