IndraLab

Statements

reach
"In this study, we identified USP13 as the first deubiquitinase that reverses PTEN poly-ubiquitination and stabilizes PTEN protein, and found that USP13 suppresses tumorigenesis and glycolysis through PTEN."
24270891
reach
"Indeed, knockdown of USP13 increased glucose uptake and glycolysis, which could be fully reversed by restoration of PTEN, as gauged by lactate production and glucose incorporation assays (XREF_FIG)."
24270891
reach
"miR-135b promoted cell proliferation and glycolysis that could be reversed by the overexpression of USP13 or PTEN."
25571954
reach
"Conversely, overexpression of USP13 suppresses tumorigenesis and glycolysis in PTEN positive but not PTEN-null breast cancer cells."
24270891